Jerry Silver Selected Research

Chondroitin Sulfate Proteoglycans

1/2020	Regulation of autophagy by inhibitory CSPG interactions with receptor PTPσ and its impact on plasticity and regeneration after spinal cord injury.
3/2018	Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury.
1/2018	The Biology of Regeneration Failure and Success After Spinal Cord Injury.
1/2018	Modulation of Receptor Protein Tyrosine Phosphatase Sigma Increases Chondroitin Sulfate Proteoglycan Degradation through Cathepsin B Secretion to Enhance Axon Outgrowth.
2/2016	Disrupting protein tyrosine phosphatase σ does not prevent sympathetic axonal dieback following myocardial infarction.
4/2015	NG2+ progenitors derived from embryonic stem cells penetrate glial scar and promote axonal outgrowth into white matter after spinal cord injury.
12/2014	Entrapment via synaptic-like connections between NG2 proteoglycan+ cells and dystrophic axons in the lesion plays a role in regeneration failure after spinal cord injury.
8/2014	Contributions of chondroitin sulfate proteoglycans to neurodevelopment, injury, and cancer.
9/2013	Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment.
10/2010	Immature astrocytes promote CNS axonal regeneration when combined with chondroitinase ABC.

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Jerry Silver Research Topics

Disease

21	Spinal Cord Injuries (Spinal Cord Injury) 01/2021 - 07/2004
8	Gliosis 01/2018 - 02/2004
5	Wounds and Injuries (Trauma) 01/2020 - 04/2006
4	Inflammation (Inflammations) 02/2012 - 08/2005
3	Cicatrix (Scar) 01/2018 - 02/2016
2	Neoplasms (Cancer) 08/2014 - 09/2013
2	Contusions 04/2012 - 07/2011
1	Peripheral Nerve Injuries 03/2021
1	Paralysis (Palsy) 11/2018
1	Multiple Sclerosis 10/2018
1	Myocardial Infarction 02/2016
1	Brain Neoplasms (Brain Tumor) 09/2013
1	Chronic Pain 02/2012
1	Hyperalgesia 02/2012
1	Pain (Aches) 02/2012
1	Crush Injuries 02/2012
1	Optic Nerve Injuries 02/2012
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2008
1	Brain Injuries (Brain Injury) 02/2008

Drug/Important Bio-Agent (IBA)

13	Chondroitin Sulfate ProteoglycansIBA 01/2020 - 04/2006
6	Proteoglycans (Proteoglycan)IBA 10/2018 - 07/2004
5	Chondroitin ABC LyaseIBA 11/2018 - 08/2005
2	Fibroblast Growth Factor 1 (FGF-1)IBA 01/2017 - 01/2015
2	Chondroitinases and Chondroitin LyasesIBA 06/2013 - 02/2012
1	mesoglycanIBA 03/2021
1	CathepsinsIBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2018
1	Protein Tyrosine PhosphatasesIBA 02/2016
1	ChondroitinIBA 02/2015
1	Leukocyte Common Antigens (CD45 Antigen)IBA 09/2013
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 09/2013
1	Capsules (Microcapsules)IBA 09/2013
1	Fibronectins (Fibronectin)IBA 02/2012
1	Serotonin (5 Hydroxytryptamine)IBA 02/2012
1	AN 12IBA 02/2012
1	oncomodulinIBA 02/2012
1	Carrier Proteins (Binding Protein)IBA 02/2012
1	Peptides (Polypeptides)IBA 10/2011
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 07/2011
1	RolipramIBA 07/2011
1	Phosphodiesterase 4 InhibitorsIBA 07/2011
1	Clodronic Acid (Clodronate)IBA 07/2011
1	Class 2 Receptor-Like Protein Tyrosine PhosphatasesIBA 10/2009
1	SteroidsIBA 02/2008
1	Methylprednisolone FDA LinkGeneric 02/2008
1	SolutionsIBA 02/2008
1	NeurocanIBA 02/2008
1	BrevicanIBA 02/2008
1	DNA (Deoxyribonucleic Acid)IBA 02/2004
1	EnzymesIBA 02/2004
1	GlycosaminoglycansIBA 02/2004

Therapy/Procedure

5	Therapeutics 01/2018 - 02/2008
2	Axotomy 08/2009 - 09/2008
1	Transjugular Intrahepatic Portasystemic Shunt 01/2018
1	Sympathectomy (Sympathectomies) 02/2016
1	Denervation 02/2016
1	Microspheres (Microsphere) 04/2012
1	Cell Transplantation 02/2008